Copper peptides are skincare ingredients that bind copper to a three-amino-acid peptide, usually called GHK-Cu or copper tripeptide-1. They are used to support the look of firmer, smoother skin. Early research is promising, but much of it comes from a small group of researchers.
What is GHK-Cu?
GHK is a peptide made of three amino acids: glycine, histidine and lysine. It binds easily to copper, which forms GHK-Cu. A 2015 review describes how the peptide is found naturally in the body and how it has been studied in skin.
What does the research show?
The research is interesting, but it needs careful reading. That review describes a placebo-controlled study in which a GHK-Cu face cream improved visible signs of ageing in 71 women over 12 weeks.
A later systematic review estimates that about 35% of the primary research includes the same two authors, who have a commercial link to the ingredient. It calls for more clinical trials, so treat large claims with caution.
How much copper peptide is in a serum?
Many brands do not say. Our Copper Peptide Serum lists copper tripeptide-1 at 0.5%, along with the percentage of every other ingredient. If a label gives no figure, its position in the ingredient list gives only a rough idea.
Where can you buy copper peptides in NZ?
Pharmacies, beauty retailers and skincare brands sell them, including our Copper Peptide Serum. Check the label says Copper Tripeptide-1, and be wary of anything sold for injection, which is a very different legal matter.
How do you use a copper peptide serum?
Keep the routine simple so you can tell how your skin responds.
- Cleanse and pat your skin dry.
- Apply a few drops to your face.
- Moisturise once the serum has settled.
- Finish with sunscreen in the morning.
What can you use with copper peptides?
Hyaluronic acid, panthenol and ceramides are easy partners. Many people keep copper peptides apart from strong vitamin C and acid products, as explained in our vitamin C guide. For scalp use, read copper peptides for hair.
Common questions
Is GHK-Cu the same as copper tripeptide-1?
Yes. GHK-Cu is the scientific shorthand and Copper Tripeptide-1 is the INCI name you will see on a cosmetic label. Both describe the peptide glycyl-histidyl-lysine bound to copper.
Why are copper peptide serums blue?
Copper gives these formulas a blue colour. The shade depends on the formula and concentration, so colour alone will not tell you how much copper peptide a product contains.
How often can I use a copper peptide serum?
Most people use a copper peptide serum once a day, morning or night, on clean skin. Start every second day if your skin reacts easily, and stop if you get lasting irritation.